P
(continuation of)
Polymorphic
light eruption
| Pompholyx | Porokeratosis
| Porphyria cutanea tarda | Portwine
stain | Pregnancy rashes
| Prickly heat (go to milaria)
| Prurigo nodularis | Pruritus
| Pruritus ani | Pruritus
vulvae | Pseudofolliculitis
barbae (razor bumps) | Psoriasis
| Purpura
| Pyoderma gangrenosum |
Pyogenic granuloma | Previous
....
POLYMORPHIC LIGHT ERUPTION
Polymorphic light eruption
(PMLE) is the most common type of true photosensitivity. It usually
affects young and middle-aged women. PMLE is more common in temperate
climates and usually occurs during spring. The skin hardens (becomes
more resistant) as the summer approaches. It is less commonly
seen in tropical countries which are sunny throughout the year,
presumably because the skin has hardened.
Cause
- Sensitivity to ultraviolet
B and occasionally ultraviolet A.
- An inherited form
of PMLE has been observed in American Indians.
Symptoms
- Pink or red papules
(bumps ) on the arms, chest or legs. The face is usually spared.
- Sometimes PMLE is
more severe and blisters may develop.
What you can do
- You should consult
a doctor.
- Reduce exposure to
the sun (see sun protection).
What the doctor
may do
- Prescribe beta carotene,
antimalarial drugs or oral steroids.
- Use PUVA
to help the skin harden and become tolerant of the sun.
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POMPHOLYX
Pompholyx or dyshidrotic
eczema is a type of eczema characterised by small deep-seated
blisters on the palms and/or soles.
- Cause
- A type of endogenous
eczema characterised
by small vesicles (blisters).
Predisposing factors
- Hyperhidrosis (sweaty palms or soles).
- Heat, whether due
to the environment or the climate.
- Allergy to chromates
and nickel in the diet.
- Stress.
Symptoms
- Small deep-seated
blisters looking like sago grains or frog spawn.
- Affects the sides
of the fingers, palms and the soles.
- Itching and burning
- As blisters dry up,
the skin becomes dry and cracked.
|
Pompholyx.
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on image for larger view |
Complications
- Deep cracks may cause
bleeding and pain.
- Secondary bacterial
infection.
What you can do
- You should consult
a doctor.
- Soak in potassium
permanganate solution for 15 minutes twice a day until the blisters
dry up.
- Do not break blisters
as this encourages bacterial infection.
- Take antihistamines
to relieve itching.
- Adopt the same measures
as for hand
eczema.
What the doctor
may do
- Prescribe topical
steroids and in
severe cases, a short course of oral steroids.
- Exclude underlying
tinea pedis which may produce an
allergic reaction consisting of blisters on the hands.
- Perform patch
tests to exclude allergy to nickel or chromate. Those found
to be allergic may benefit from nickel- or chromate- free diets.
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POROKERATOSIS
Porokeratosis refers
to a group of 3 rare skin disorders:
- Porokeratosis of Mibelli,
- Disseminated superficial
actinic porokeratosis.
- Porokeratosis plantaris
or palmaris.
Cause
- Inherited by autosomal
dominant transmission which means only one parent need to be
affected and the offsprings have a 1 in 2 chance of inheriting
the defect and developing the disorder.
Symptoms
- Porokeratosis of
Mibelli.
-
- Thinned depressed
area with a raised slowly enlarging ridged border.
- My occur singly or
in groups over a segment of the skin.
- Usually appears in
early childhood and may enlarge to several centimeters in size.
- Disseminated superficial
actinic porokeratosis
-
- Affects the sun-exposed
skin.
- Multiple small, slightly
depressed red or brownish spots with a ridged border.
- Often itchy.
- Affects young adults.
- Porokeratosis palmaris
or plantaris
-
- Similar to disseminated
superficial actinic porokeratosis except that they are confined
to the palms and soles.
- Usually occurs in
the teens.
Complications
- Squamous cell cancer
may occasionally develop in porokeratosis of Mibelli.
What you can do
- You should consult
the doctor.
- Disseminated superficial
actinic porokeratosis is induced by sunlight. Therefore, use
physical protection and sunscreens (see sun-protection).
What the doctor
may do
- Follow-up, especially
in cases of porokeratosis of Mibelli.
- Treat with 5 fluorouracil
cream.
- Small lesions may
be removed surgically or destroyed with the carbon
dioxide laser or with electrosurgery.
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PORPHYRIA
CUTANEA TARDA
Porphyria cutanea tarda
is a rare photosensitive (light-sensitive) skin disorder.
Cause
- A defect in a liver
enzyme (uroporphyrinogen decarboxylase) that is involved in the
synthesis of the haem (red pigment in haemoglobin). This results
in abnormal levels of porphyrins in the skin, making it sensitive
to light.
Aggravating factors
- Alcohol.
- Oral contraceptives.
- Excessive intake of
iron.
- Exposure to polychlorinated
hydrocarbons (found in some pesticides), chlorinated phenols
, tetra-chlorodibenzo-p-dioxin.
Symptoms
- Blisters on the back
of the hands and the forearms.
- The blisters break
to form small ulcers which heal with scarring and milia formation
(milia are small whitehead-like cysts).
- Occasionally the skin
may become brown and hardened (scleroderma-like) on the face,
neck and "v" of the chest.
- There may be increased
facial hair.
What you can do
- You should consult
the doctor.
- Protect the skin against
the sun (see sun protection).
- Avoid alcohol, oral
contraceptives and iron supplements.
What the doctor
may do
- Perform a skin
biopsy.
- Examine the urine
and stools for porphyrins. Urine containing porphyrins give a
coral red fluorescence when illuminated with a Wood's lamp.
- Perform blood tests
to check on the haemoglobin level, iron stores and liver enzymes.
- Perform phlebotomy
(blood-letting) to remove haemoglobin.
- Prescribe anti-malarial
medication to promote urinary excretion or porphyrins.
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PORTWINE
STAIN
The portwine stain
or naevus flammeus is a vascular birthmark. It may be found on
any part of the body, especially on one side of the face where
it can be cosmetically, very distressing. Portwine stains are
present at birth and persist for life.
Cause
- Abnormal development
of the blood vessels in the skin.
Symptoms
- Pink or purple patch
that looks like the stain left by rich red port wine.
- Usually unilateral
(one-sided).
- The colour may be
become deeper purple when the child cries.
Complications
- The portwine stain
on one side of the face may occasionally be associated with with
underlying malformation of the blood vessels inside the skull,
epilepsy (fits) and glaucoma. This condition is known as Sturge-Weber
syndrome.
- Portwine stains affecting
the extremity may occasionally be associated with an overgrowth
of the underlying bone and soft tissue (a condition known as
Klippel-Trenaunay-Weber syndrome).
What you can do
- Leave alone or use
cosmetic camouflage.
- You should consult
a doctor.
What the doctor
may do
- Treat with vascular
lasers.
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PREGNANCY RASHES
Pre-existing skin conditions
such as acne, eczema or psoriasis may sometimes get worse during
pregnancy. However, there are other disorders that are specifically
caused by pregnancy and are described below:
- Spangler's dermatitis
(papular dermatitis of pregnancy).
-
- Groups of red papules
(bumps) with scratched-off crusted tops.
- Fade after pregnancy.
- Heal with a dark stain.
- Associated with 30%
risk of stillbirth or spontaneous abortion.
- Treatment is with
oral steroids.
- May recur with subsequent
pregnancies.
-
- Pruritic urticarial papules
and plaques of pregnancy (PUPPP)
-
- Red papules (bumps)
plaques (elevated patches) that look like urticaria (hives).
- They usually start
on the abdomen, especially along the stretch marks and spread
to the thighs, buttocks and arms.
- They usually appear
during the last 3 months of pregnancy.
- Itch is very severe
and often disturbs sleep.
- Not associated with
any adverse effects on the baby.
- Clears with delivery
of the child.
- Usually affects first
time pregnant women.
- Usually does not recur
with subsequent pregnancies. If it does, it is usually less severe.
- Treatment is with
oral antihistamines
and topical steroids.
Oral steroids may
be used in severe cases.
|
Pruritic urticarial papules
and plaques of pregnancy (PUPPP).
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on image for larger view |
- Immune progesterone
dermatitis of pregnancy
- Papules (pimply bumps)
and pustules (pusheads) that resemble acne on the buttocks and
limbs.
- Occurs during the
first trimester of pregnancy.
- May recur with subsequent
pregnancies.
- Treatment is with
oestrogens (one of the female hormones).
-
- Pruritus
gravidarum
- Itching during the
third trimester which clears after birth.
- Recurs with subsequent
pregnancies.
-
- Melasma (mask of pregnancy).
- Striae
distensae
(stretch marks).
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PRURIGO NODULARIS
This is a nodular form
of lichen simplex chronicus.
It may affect adults of any age but is more common in the elderly.
Cause
- The cause is unknown
but it may have something to do with the sensory nerves in the
skin which appear to be hypertrophied (enlarged) and possibly
oversensitive.
- Patients with a personal
or family history of atopic dermatitis, asthma and hay fever
are more prone to develop prurigo nodularis.
Symptoms
- Intensely itchy nodules
(swellings) which cause the person to scratch and dig at their
skin.
- The tops are often
scratched off and topped by a crust or dried blood.
- Prurigo nodularis
usually affects the neck and limbs.
|
Prurigo nodules.
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on mage fo larger view |
Complications
- Secondary bacterial
infection.
What you can do
- You should consult
a doctor.
- Avoid scratching or
picking the nodules as this usually cause the nodules to enlarge.
What the doctor
may do
- Treat with topical
steroids or intralesional steroids
injections or liquid nitrogen.
- Prescribe antihistamines
and occasionally, antidepressants.
- Treat with PUVA
phototherapy.
- A gluten free diet
may help to protect the intestine and improve the skin.
- TOP
-
PRURITUS
Pruritus is the medical
term for itching. Pruritus may be localised to one area such
as the vagina (pruritus vulvae)
or around the anus (pruritus ani)
or it may be generalised (generalised
pruritus).
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PRURITUS
ANI
Pruritus ani is the
medical term for itching around the anus.
Causes
- Faecal soiling due
to haemorrhoids, fissures (tears) and fistulae (tunnels connecting
the rectum to the outside skin).
- Skin problems affecting
the area such as atopic dermatitis,
seborrhoeic dermatitis,
psoriasis, lichen
sclerosus et atrophicus and fungal infection (see tinea).
- Irritation or allergy
to antiseptics, scented toilet paper or medicines for haemorrhoids
(piles).
- Threadworm infestation
(in children).
- Diabetes.
- Diet of highly seasoned
foods.
- Idiopathic (of unknown
cause).
What you can do
- You should consult
a doctor.
- Observe careful anal
hygiene; clean thoroughly after each bowel movement. Wash the
area with water after bowel movement or wipe the area with cotton
moistened with water.
- Avoid strong antiseptics.
- Wear loose fitting
cotton underwear.
- Avoid highly seasoned
foods.
- Avoid constipation.
- Take antihistamines
to relieve itching. Resist scratching.
What the doctor
may do
- Diagnose the underlying
cause and treat accordingly.
- Prescribe mild topical
steroids.
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PRURITUS
VULVAE
Pruritus vulvae is
the medical term for itching of the vaginal area.
Causes
- Candidiasis.
- Allergy or irritation
caused by contraceptives, deodorants and douches.
- Threadworms infestations
(in young girls).
- Skin diseases affecting
the area such as atopic dermatitis,
psoriasis, lichen
simplex chronicus, seborrhoeic
dermatitis, fungal infection (see tinea)
and lichen sclerosus
et atrophicus.
- Menopause which causes
a degenerative condition of the vagina known as senile or atrophic
vaginitis.
What you can do
- You should consult
a doctor.
- Use warm water or
very mild soap to clean.
- Keep the area cool,
avoid nylon underwear.
- Take antihistamines
to relieve itching. Try not to scratch.
What the doctor
may do
- Determine the cause
and treat accordingly.
- Prescribe mild topical
steroids.
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PSEUDOFOLLICULITIS BARBAE
Pseudofolliculitis
barbae or razor bumps is commonly seen in men with stiff or curly
hairs, especially black men.
- Causes
- Ingrown hairs due
to stiff hairs piercing the follicular canal or due to curly
hairs re-entering the skin and causing inflammation.
Symptoms
- Papules (pimply bumps)
and pustules around the hair follicles.
- May be itchy or painful.
- Usually affects the
scalp, pubic and beard areas.
Complications
- Scarring.
What you can do
- You should consult
a doctor.
- Switch to electric
razors if you have pseudofolliculitis barbae or grow a beard.
- What the doctor
may do
- Treat with oral or
topical antibiotics.
- Prescribe mild steroid
creams to reduce the inflammation.
- Remove the in-grown
hairs.
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PSORIASIS
Psoriasis is a chronic
skin disorder affecting about 1 - 2% of the population. It usually
begins between the ages of 15 and 30 years and tends to run in
families. Psoriasis runs a very protracted course with periods
of exacerbations and remissions and there is no permanent cure.
However, treatment is available to control the disease and permit
a productive life.
Causes
- The cause is unknown
but in psoriasis the skin cells are dividing faster than normal,
resulting in a scaly thickening of the skin. Fifty per cent of
those affected give a family history of psoriasis, suggesting
that genetic factors may play a role. If one parent is affected,
the offspring has a 1 in 4 chance of developing psoriasis.
Precipitating factors
- Stress.
- Streptococcal sorethroat.
- Drugs such as beta
blockers (used to treat high blood pressure), lithium (used to
treat manic-depressive states) and antimalarial medicines.
- Alcohol.
- Stopping systemic
steroids.
Symptoms
- Well-defined pink
patches with characteristic, silvery white scales.
- Affects any part of
the body, especially on the elbows, knees, near the base of the
spine and on the scalp.
- Usually symmetrically
located, that is on more or less identical sites on each side
of the body.
- Red glazed patches
in the body fold areas such as the armpits and groins.
- Nail changes in the
form of pitting, brown spots resembling oil stains on a paper
bag, onycholysis and thickening
or crumbling of the nail plate may be seen.
- Itching may or may
not be present.
- Palmoplantar pustulosis
- is a form of pustular psoriasis that affects the hands and
feet. It may also cause the skin to crack and bleed.
|
Psoriasis.
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on image for larger view |
Complications
- Psoriasis may spread
to involve the whole body, causing an erythroderma.
This type of psoriasis is called erythrodermic psoriasis.
- Psoriasis may become
pustular (with pusheads) all over the body. This is called generalised
pustular psoriasis. When this is accompanied by fever and malaise
(feeling of illness), the term von Zumbusch's pustular psoriasis
is used.
- Psoriatic arthritis
occurs in 10% of cases.
What you can do
- You should consult
a doctor.
- Avoid scratching as
psoriasis tends to develop at sites of skin injury.
- Apply moisturisers
after baths to reduce flakiness and roughness.
- Avoid strong topical
medicaments because they can make psoriasis worse and cause it
to develop into an erythroderma
or become pustular.
- Avoid obesity as this
may cause psoriasis to develop in the body folds.
- Try to get some sunlight
(not sunburn) on the skin as this helps to clear psoriasis.
- Confront and deal
with stresses.
- Maintain a positive
outlook on life.
- Maintain good physical
health by avoiding drug abuse, alcohol and smoking.
What the doctor
may do
- Prescribe topical
steroids, tar preparations, anthralin or dithranol (a tar derivative)
and calcipotriol, a vitamin D-like compound.
- Prescribe oral methotrexate
(an immunosuppressive
drugs), acitretin (an oral retinoid)
or cyclosporin (an immunosuppressive
drugs used to prevent the rejection of transplanted organs)
in resistant or extensive cases.
- Start phototherapy
(light treatment) using tar and ultraviolet-B (Geokerman regimen)
or anthralin and UVB (Ingram regime) or PUVA.
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PURPURA
Purpura is caused by
the leakage of blood from the vessels into the skin.
-
- Thrombocytopaenic
purpura caused by a deficiency in the number of platelets (a
type of white blood cells that plug up any holes in blood vessels
and stop bleeding). Causes include:
-
- Autoimmune (self-allergy)
- Drugs.
- Infections, including
dengue haemorrhagic fever.
- Bone marrow abnormality.
- Enlarged spleen.
- Non-thrombocytopaenic
purpura in which the number of platelets are normal. This type
of purpura may be due to:
-
- Drugs.
- Coagulation defects
(deficiency of clotting factors in the blood)
- Vasculitis.
- Weakening of the blood
vessel walls due to ageing and/or sun-damage (senile purpura)
or overuse of topical and systemic steroids
(steroid purpura).
Symptoms
- Red or purplish haemorrhagic
patches which do not disappear when pressed.
|
Senile purpura.
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on image for larger view |
What you can
do
- You should consult
a doctor.
What the doctor
may do
- Determine the cause
and treat accordingly.
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PYODERMA GANGRENOSUM
This is a rare ulcerative
skin condition that may be associated with internal disorders.
- Cause
- May be a hypersensitivity
reaction to underlying disorders such as:-
-
- Inflammatory bowel
disease such as Crohn's disease and ulcerative colitis.
- Rheumatoid arthritis.
- Chronic active hepatitis.
- Haematological abnormalities.
Symptoms
- Begins as one or more
red papules (bumps) or pustules (pusheads) that break down rapidly
to form ulcers.
- The ulcers enlarge
several centimeters a day and have a bluish or purple undermined
edge.
- Pain is often severe.
|
Pyoderma gangrenosum.
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on image for larger view |
Complications
- Very rarely, pyoderma
gangrenosum runs a very aggressive course, affecting nerves and
resulting in fatalities. This aggressive form is sometimes called
malignant pyoderma gangrenosum.
What you can do
- You should consult
a doctor.
- Clean the ulcer gently
and cover with a dressing.
What the doctor
may do
- Treat with topical,
intralesional
or oral steroids,
sulphapyridine, methotrexate (an immunosuppressive
drug), minocycline (an antibiotic), antileprosy drugs such
as dapsone and clofamazine. Cyclosporin (an immunosuppressive
drug) may also be used.
- Pyoderma gangrenosum
is generally very difficult to treat. The underlying cause should
be identified and treated.
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PYOGENIC GRANULOMA
Pyogenic granulomas
or proud flesh are rapidly developing vascular growths appearing
at the sites of injury.
Cause
- Non-cancerous proliferation
of the blood vessels in reaction to injury.
Symptoms
- Occurs anywhere especially
on the lips, gums, digits, face and scalp.
- Soft raspberry-like
growth.
- Fragile, bleeds with
minor trauma.
|
Pyogenic granuloma
Click
on image for larger view |
What you can
do
- You should consult
a doctor.
- If bleeding occurs,
apply pressure for 5 minutes.
What the doctor
may do
- Destroy with liquid
nitrogen, electrosurgery,
curettage, carbon
dioxide laser or a vascular
laser.
- Recurrence after treatment
is common, requiring retreatment.
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