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Non specific genital
infection
Other names |
Non-specific urethritis (NSU), nongonococcal
urethritis (NGU), non-specific cervicitis, chlamydial infection. |
Causes |
Nonspecific genital infection is
an infection of the urethra or cervix (in the female) where a
cause cannot be demonstrated on routine investigations. With
special investigations, however, the causes identified include:-
- Chlamydia trachomatis 30 -50%
- Ureaplasma urealyticum 10 - 40%
- Others 20 -30%
- Trichomoniasis
- Candidiasis
- Wart, herpes or primary syphilis of the urethra
- Foreign body in the urethra
- Urethral stricture or narrowing
- Allergy
- Unknown (true NSU/NSGI)
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Distribution |
Worldwide |
Tansmission |
- Sexual in most cases.
- Mother to child, usually during
delivery.
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Incubation |
1 - 4 weeks. |
Symptoms |
Infection in men usually developes
in the urethra causing a urethritis. Hence, infection is commonly
known as nonspecific urethritis (NSU) or nongonococcal
urethritis (NGU). In women, infection usually occurs in the
cervix and is called nonspecific cervicitis or just nonspecific
genital infection (NSGI).
NSU/NGU
- Burning or itching during urination.
- Milky discharge, particularly noticeable in the morning.
- Stains on the underwear.
- No symptoms.
NSGI/Nonspecific cervicitis
- Itching and burning of the vagina
- Slight vaginal discharge.
-No symptoms (the majority).
NB These symptoms are often not characteristic so
NSGI is often made on the basis of the male partner having
NSU. |
Diagnosis |
- Microscopic examination of secretions
for pus.
- Excluding gonorrhoea which causes
similar symptoms.
- Where available, culture tests for
Chlamydia trachomatis and Ureapalsma urealyticum.
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Treatment |
Antibiotics by mouth (penicillin
and antibiotic injections are ineffective). |
Complications |
- In men,
- Recurrent or chronic NSU
- Reiters disease
Symptoms:
- Arthritis (joint inflammation).
- Conjunctivitis (eye inflammation).
- Rashes.
- Epididymitis - This is an
inflammation of the epididymis of storehouse for sperm. It may
cause infertility.
Symptoms:
- Pain and swelling of the testis.
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- In women,
- Pelvic inflammatory disease (PID)
- This is caused by infection spreading into the uterus and Fallopian
tubes. PID may result in infertility.
Symptoms:
- Lower abdominal pain.
- Backache
- Menstrual irregularities.
- Low-grade fever.
In the newborn,
- Neonatal (newborn) conjuctivitis
- Eye infection caused by infected vaginal secretions contaminating
the babys eyes. Chlamydia trachomatis is usually the cause.
- Neonatal (newborn pneumonia)
- Lung infection caused by inhalation or ingestion of infected
vagina secretions during delivery. Chlamydia trachomatis
is the cause.
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Comments |
NSGI and gonorrhoea may occur together.
However, gonorrhoea has a shorter incubation period so its symptoms
appear first. The symptoms of NSU, on the other hand appear 1
-2 weeks later, by which time gonorrhoea would have been
treated and cleared. NSU occuring after gonorrhoea is termed
postgonococcal urethritis (PGU). |
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